According to a recent study, animals with this neurodegenerative condition can have their immune systems strengthened and their cognitive abilities improved by exposure to a certain smell. This opens the door for innovative therapy strategies that use olfactory stimulation and training to counteract or lessen the effects of Alzheimer’s and other central nervous system illnesses.
Through experiments on rats suffering from Alzheimer’s disease, Spanish researchers from the Cima University of Navarra have demonstrated that inhaling menthol enhances cognitive performance. According to their research, this substance’s frequent, brief exposure can regulate the immune response and fend off the typical cognitive deterioration linked to this neurodegenerative condition.
The researchers studied how menthol functions and discovered that the presence of the smell caused interleukin-1-beta (IL-1b) levels to drop. A crucial protein in the inflammatory response is IL-1b. Additionally, scientists found that the affected mice’s cognitive abilities improved when they suppressed this protein using a drug licenced for treating several autoimmune disorders.
This study emphasises the therapeutic potential of odours and immune modulators. It also opens the door to the development of treatments for Alzheimer’s and other central nervous system illnesses that involve olfactory system stimulation and training. The findings of this study were published in the most recent edition of Frontiers in Immunology.
Complex connections between different types of nerve cells, immune cells, and neural stem cells are essential for maintaining the brain’s functional equilibrium. Numerous research have examined the immunomodulatory and neurological effects of odorants in this intricate web of interactions. A association between the loss of scent and the start of Alzheimer’s disease has also been demonstrated in other earlier studies.
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